Process Development

Process development is where scientific precision meets reliable execution.
At LOTTE Biologics, our process development services are built on a phase-appropriate, science-driven approach designed to ensure consistency, scalability, and manufacturability.

Guided by our experienced upstream and downstream specialists, we support end-to-end program execution — from early development through technology
transfer — with proven expertise across multiple cell lines and biologic modalities.

Upstream Process Development

We tailor upstream development to each molecule, optimizing for robust performance and efficient scale-up

Molecule Information /
Cell Bank Transfer
Basal Media Screening
in Shake Flask
Feed Media Screening in
Shake Flask
Process Optimization
in Ambr 250™
Bench-Scale Process
Verification

Downstream Process Development

We tailor downstream development to product-specific purification needs, balancing quality, recovery, and process robustness.

Preparation for
DSP Development
Column Process
Development
Viral Filtration
UF/DF
Process
Verification

Why Partner with Us?

30+ Years of Combined
Development Experience
Expertise Across
Diverse Modalities*
Molecule-Informed Process
Development
Critical Parameter
Identification and Control
Integrated Upstream and
Downstream Strategy
Designed for Scale-Up
and Technology Transfer

* Across diverse protein modalities including mAb, Bispecific and Fusion protein and multiple CHO cell lines, including CHO-S, CHO-DG44, CHO-K, and NS0

Speak to Our Experts?

Process Development | LOTTE BIOLOGICS